Intracellular nitric oxide delivery from stable NO-polymeric nanoparticle carriers.
نویسندگان
چکیده
The encapsulation of S-nitrosoglutathione into polymeric nanoparticles substantially improves NO stability in aqueous media without affecting the efficacy of intracellular delivery. The combination of nano-NO delivery and chemotherapy has been found to enhance antitumour activity of chemotherapeutics, as demonstrated using preliminary in vitro experiments with neuroblastoma cells.
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عنوان ژورنال:
- Chemical communications
دوره 49 39 شماره
صفحات -
تاریخ انتشار 2013